Meniere's Disease
July 2023 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Meniere's Disease abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Meniere's Disease. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Meniere's Disease. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Meniere's Disease every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Efficacy of Intratympanic OTO-104 for the Treatment of Ménière's Disease: The Outcome of Three Randomized, Double-Blind, Placebo-Controlled Studies.
Authors:Phillips J, Mikulec AA, Robinson JM, Skarinsky D, Anderson JJ
Institution:Department of Otolaryngology, Norfolk & Norwich University Hospitals NHS Foundation Trust, Norwich, UK.; Otonomy, Inc., San Diego, CA.
Journal:Otol Neurotol. 2023 Jul 1;44(6):584-592. doi: 10.1097/MAO.0000000000003886. Epub 2023 Apr 22.

2:Endolymphatic Duct Blockage as a Surgical Treatment Option for Ménière's Disease.
Authors:Schenck AA, Saliba I, Kruyt JM, van Benthem PP, Blom HM
Institution:Department of Otorhinolaryngology, Haga Hospital; Department of Otorhinolaryngology, Leiden University Medical Centre; J.Schenck@hagaziekenhuis.nl.; Department of Otorhinolaryngology, Haga Hospital; Department of Otorhinolaryngology, Leiden University Medical Centre; Department of Otorhinolaryngology, Antwerp University Hospital.
Journal:J Vis Exp. 2023 Apr 28;(194). doi: 10.3791/65061.

3:Perspectives of Emergency Physicians, Primary Care Physicians, and Otolaryngologists on the Diagnosis and Treatment of Acute Vertigo.
Authors:Dede MN, Başoğlu Y, Yilmaz B, Şerbetçioğlu MB
Institution:Graduate School of Health Sciences, Istanbul Medipol University, Turkey.
Journal:Am J Audiol. 2023 Jun;32(2):289-302. doi: 10.1044/2022_AJA-22-00146. Epub 2023 Mar 30.

4:Lifestyle and dietary interventions for Ménière's disease.
Authors:Webster KE, George B, Lee A, Galbraith K, Harrington-Benton NA, Judd O, Kaski D, Maarsingh OR, MacKeith S, Murdin L, Ray J, Van Vugt VA, Burton MJ
Institution:Cochrane ENT, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.; Cochrane UK, Oxford, UK.
Journal:Cochrane Database Syst Rev. 2023 Feb 27;2(2):CD015244. doi: 10.1002/14651858.CD015244.pub2.

5:Intratympanic corticosteroids for Ménière's disease.
Authors:Webster KE, Lee A, Galbraith K, Harrington-Benton NA, Judd O, Kaski D, Maarsingh OR, MacKeith S, Ray J, Van Vugt VA, Westerberg B, Burton MJ
Institution:Cochrane ENT, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.; Cochrane UK, Oxford, UK.
Journal:Cochrane Database Syst Rev. 2023 Feb 27;2(2):CD015245. doi: 10.1002/14651858.CD015245.pub2.

6:Intratympanic gentamicin for Ménière's disease.
Authors:Webster KE, Galbraith K, Lee A, Harrington-Benton NA, Judd O, Kaski D, Maarsingh OR, MacKeith S, Ray J, Van Vugt VA, Burton MJ
Institution:Cochrane ENT, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.; Cochrane UK, Oxford, UK.
Journal:Cochrane Database Syst Rev. 2023 Feb 27;2(2):CD015246. doi: 10.1002/14651858.CD015246.pub2.

7:Systemic pharmacological interventions for Ménière's disease.
Authors:Webster KE, Galbraith K, Harrington-Benton NA, Judd O, Kaski D, Maarsingh OR, MacKeith S, Ray J, Van Vugt VA, Burton MJ
Institution:Cochrane ENT, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.; Cochrane UK, Oxford, UK.
Journal:Cochrane Database Syst Rev. 2023 Feb 23;2(2):CD015171. doi: 10.1002/14651858.CD015171.pub2.

8:Surgical interventions for Ménière's disease.
Authors:Lee A, Webster KE, George B, Harrington-Benton NA, Judd O, Kaski D, Maarsingh OR, MacKeith S, Ray J, Van Vugt VA, Burton MJ
Institution:Department of Otolaryngology - Head and Neck Surgery, University of Toronto, Toronto, Canada.; Cochrane UK, Oxford, UK.
Journal:Cochrane Database Syst Rev. 2023 Feb 24;2(2):CD015249. doi: 10.1002/14651858.CD015249.pub2.

9:Positive pressure therapy for Ménière's disease.
Authors:Webster KE, George B, Galbraith K, Harrington-Benton NA, Judd O, Kaski D, Maarsingh OR, MacKeith S, Ray J, Van Vugt VA, Burton MJ
Institution:Cochrane ENT, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.; Cochrane UK, Oxford, UK.
Journal:Cochrane Database Syst Rev. 2023 Feb 23;2(2):CD015248. doi: 10.1002/14651858.CD015248.pub2.

10:Functional and Molecular Markers for Hearing Loss and Vertigo Attacks in Meniere's Disease.
Authors:Yang CH, Yang MY, Hwang CF, Lien KH
Institution:Department of Otolaryngology-Head & Neck Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan.; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Journal:Int J Mol Sci. 2023 Jan 28;24(3):2504. doi: 10.3390/ijms24032504.

11:Correlations of Clinical and Audio-Vestibulometric Findings with Coexisting Anxiety and Depression in Ménière's Disease Patients.
Authors:Subasi B, Yildirim N, Akbey ZY, Karaman NE, Arik O
Institution:Department of Otorhinolaryngology, Kutahya Health Sciences University Medical Faculty, Kutahya, Turkey.; Department of Biostatistics, Kutahya Health Sciences University Medical Faculty, Kutahya, Turkey.
Journal:Audiol Neurootol. 2023;28(2):75-83. doi: 10.1159/000528421. Epub 2023 Jan 19.

12:Endolymphatic sac decompression effect on secondary symptoms of Meniere's disease.
Authors:Conway RM, Babu SC, Mallany P, Weymon A, Wilkerson BJ
Institution:Department of Otolaryngology - Head and Neck Surgery, Ascension Macomb-Oakland Hospital, Madison Heights, MI, USA. Electronic address: Conwayr4@msu.edu.; Otology, Neurotology, and Lateral Skull Base Surgery, University of South Carolina - Greenville, Greenville, SC, USA.
Journal:Am J Otolaryngol. 2023 Mar-Apr;44(2):103777. doi: 10.1016/j.amjoto.2022.103777. Epub 2022 Dec 26.

13:Genetic advances in Meniere Disease.
Authors:Dai Q, Long L, Zhao H, Wang R, Zheng H, Duan M
Institution:Department of Otorhinolaryngology-Head and Neck Surgery, West China Hospital of Sichuan University, Chengdu, 610041, Sichuan, China.; Department of Otolaryngology-Head and Neck, Department of Clinical Science, Intervention and Technology, Karolinska University Hospital, Karolinska Institute, 17176, Stockholm, Sweden. maoli.duan@ki.se.
Journal:Mol Biol Rep. 2023 Mar;50(3):2901-2908. doi: 10.1007/s11033-022-08149-8. Epub 2022 Dec 24.

14:Vestibular migraine or Meniere's disease: a diagnostic dilemma.
Authors:Chen JY, Guo ZQ, Wang J, Liu D, Tian E, Guo JQ, Kong WJ, Zhang SL
Institution:Department of Otorhinolaryngology, Tongji Medical College, Union Hospital, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan City, 430022, Hubei Province, People's Republic of China. sulin_zhang@hust.edu.cn.
Journal:J Neurol. 2023 Apr;270(4):1955-1968. doi: 10.1007/s00415-022-11532-x. Epub 2022 Dec 23.

15:Public Perception of Ménière's Disease: A Social Media Analysis.
Authors:Hamdi OA, Bellinger JR, Wright GP, Churnin IT, Strumpf AM, Casazza GC, Kesser BW
Institution:University of Virginia School of Medicine, Charlottesville, VA.
Journal:Otol Neurotol. 2023 Feb 1;44(2):177-182. doi: 10.1097/MAO.0000000000003790. Epub 2022 Dec 21.

16:Cognitive function in Meniere's disease.
Authors:Eraslan Boz H, Kırkım G, Koçoğlu K, Çakır Çetin A, Akkoyun M, Güneri EA, Akdal G
Institution:Department of Neurology, Unit of Neuropsychology, Dokuz Eylul University School of Medicine, Izmir, Turkiye.; Department of Neurosciences, Dokuz Eylul University, Institute of Health Sciences, Izmir, Turkiye.
Journal:Psychol Health Med. 2023 Apr;28(4):1076-1086. doi: 10.1080/13548506.2022.2144637. Epub 2022 Nov 11.

17:Is endolymphatic sac surgery an efficient treatment of Menière's disease patients? A systematic literature search and meta-analysis.
Authors:Szott FA, Westhofen M, Hackenberg S
Institution:Department of Otolaryngology-Head and Neck Surgery, RWTH Aachen University Hospital, Pauwelsstr. 30, 52074, Aachen, Germany. fszott@ukaachen.de.
Journal:Eur Arch Otorhinolaryngol. 2023 Mar;280(3):1119-1128. doi: 10.1007/s00405-022-07580-8. Epub 2022 Oct 8.

18:Bifenestral surgical and chemical labyrinthectomy, a new effective ablative surgical approach to intractable vertigo in Ménière disease elderly patients.
Authors:Salvinelli F, Bonifacio F, Trivelli M, Greco F, Frari V, Amadio D
Institution:Research Unit of Otorhinolaryngology, Campus Biomedico Universty, Rome.; Department of Otorhinolaryngology, Fondazione Policlinico Campus Biomedico, Via Alvaro del Portillo n. 200 - 00128 Roma.
Journal:Acta Otorrinolaringol Esp (Engl Ed). 2023 May-Jun;74(3):169-174. doi: 10.1016/j.otoeng.2022.09.001. Epub 2022 Sep 30.

19:Cognitive functions in episodic vestibular disorders: Meniere's disease and vestibular migraine.
Authors:Demirhan MA, Celebisoy N
Institution:Department of Clinical Neuroscience, Ege University Institute of Health Sciences, Izmir, Turkey.
Journal:J Vestib Res. 2023;33(1):63-70. doi: 10.3233/VES-220025.

20:Vestibular and audiometric results after endolymphatic mastoid shunt surgery in patients with Menière's disease.
Authors:Spiegel JL, Stoycheva I, Weiss BG, Bertlich M, Rader T, Canis M, Ihler F
Institution:Department for Otorhinolaryngology, University Hospital, Ludwig-Maximilians-Universitat Munchen, Marchioninistr. 15, 81377, Munich, Germany. jennifer.spiegel@med.uni-muenchen.de.
Journal:Eur Arch Otorhinolaryngol. 2023 Mar;280(3):1131-1145. doi: 10.1007/s00405-022-07582-6. Epub 2022 Aug 15.

21:Increased Risk of Injury in Ménière's Disease and Effects of Treatment: Population-Based Retrospective Cohort Study.
Authors:Wu PL, Lin HC, Chien WC, Chung CH, Chen JW
Institution:Department of Medical Education and Research, Cardinal Tien Hospital, New Taipei City.
Journal:Otolaryngol Head Neck Surg. 2023 Mar;168(3):443-452. doi: 10.1177/01945998221106628. Epub 2023 Jan 27.

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