Spondylolisthesis
January 2019 Issue
 
 
 

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Spondylolisthesis abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Spondylolisthesis. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Spondylolisthesis. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Spondylolisthesis every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.



1:Spino-pelvic alignment, balance, and functional disability in patients with low-grade degenerative lumbar spondylolisthesis.
Authors:Chuang CY, Liaw MY, Wang LY, Huang YC, Pong YP, Chen CW, Wu RW, Lau YC
Institution:Department of Physical Medicine and Rehabilitation, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan ROC.
Journal:J Rehabil Med. 2018 Nov 7;50(10):898-907. doi: 10.2340/16501977-2489.

2:Degenerative Lumbar Spondylolisthesis: Biochemical Aspects and Evaluation of Stabilization Surgery Extent in Terms of Adjacent Segment Disease Theory.
Authors:Sutovsky J, Sutovska M, Kocmalova M, Kazimierova I, Pappova L, Benco M, Grendar M, Bredvold HH, Miklusica J, Franova S
Institution:Neurosurgery Clinic, Martin University Hospital, Jessenius Faculty of Medicine, Comenius University, Martin, Slovakia.; Department of Pharmacology, Jessenius Faculty of Medicine, Comenius University, Martin, Slovakia. Electronic address: martinka.sutovska@gmail.com.; Department of Pharmacology, Jessenius Faculty of Medicine, Comenius University, Martin, Slovakia; BioMed, Martin's Biomedical Center, Jessenius Faculty of Medicine, Comenius University, Martin, Slovakia.; Transplant and Vascular Surgery Clinic, Martin University Hospital, Jessenius Faculty of Medicine, Comenius University, Martin, Slovakia.
Journal:World Neurosurg. 2019 Jan;121:e554-e565. doi: 10.1016/j.wneu.2018.09.163. Epub 2018 Sep 29.

3:Reduction of Slippage Influences Surgical Outcomes of Grade II and III Lumbar Isthmic Spondylolisthesis.
Authors:Shi L, Chen Y, Miao J, Shi J, Chen D
Institution:Spine Center, Department of Orthopaedics, Changzheng Hospital, Second Military Medical University No. 415, Shanghai, China. Electronic address: chen_spine@126.com.
Journal:World Neurosurg. 2018 Dec;120:e1017-e1023. doi: 10.1016/j.wneu.2018.08.217. Epub 2018 Sep 7.

4:Comparison of minimally invasive decompression and combined minimally invasive decompression and fusion in patients with degenerative spondylolisthesis with instability.
Authors:Hayashi K, Toyoda H, Terai H, Hoshino M, Suzuki A, Takahashi S, Tamai K, Ohyama S, Hori Y, Yabu A, Nakamura H
Institution:Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan. Electronic address: h-toyoda@msic.med.osaka-cu.ac.jp.
Journal:J Clin Neurosci. 2018 Nov;57:79-85. doi: 10.1016/j.jocn.2018.08.032. Epub 2018 Aug 25.

5:Spinopelvic Sagittal Alignment after Microendoscopic Laminotomy in Patients with Lumbar Degenerative Spondylolisthesis.
Authors:Dohzono S, Toyoda H, Hori Y, Takahashi S, Suzuki A, Terai H, Nakamura H
Institution:Department of Orthopaedic Surgery, Yodogawa Christian Hospital, Osaka, Japan.; Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
Journal:J Neurol Surg A Cent Eur Neurosurg. 2018 Nov;79(6):479-485. doi: 10.1055/s-0038-1666847. Epub 2018 Jul 30.

6:Transforaminal Endoscopic Decompression in the Setting of Lateral Lumbar Spondylolisthesis.
Authors:Telfeian AE, Oyelese A, Fridley J, Gokaslan ZL
Institution:Department of Neurosurgery, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA. Electronic address: atelfeian@Lifespan.org.
Journal:World Neurosurg. 2018 Sep;117:321-325. doi: 10.1016/j.wneu.2018.06.106. Epub 2018 Jun 22.

7:The Challenge of Creating Lordosis in High-Grade Dysplastic Spondylolisthesis.
Authors:Hoel RJ, Brenner RM, Polly DW Jr
Institution:Department of Orthopaedic Surgery, University of Minnesota, 2450 Riverside Avenue South, Suite R200, Minneapolis, MN 55454, USA. South, Suite R200, Minneapolis, MN 55454, USA. South, Suite R200, Minneapolis, MN 55454, USA; Department of Neurosurgery, University of Minnesota, 2450 Riverside Avenue South, Suite R200, Minneapolis, MN 55454, USA. Electronic address: pollydw@umn.edu.
Journal:Neurosurg Clin N Am. 2018 Jul;29(3):375-387. doi: 10.1016/j.nec.2018.03.006.

8:Long-Term Minimum Clinically Important Difference in Health-Related Quality of Life Scores After Instrumented Lumbar Interbody Fusion for Low-Grade Isthmic Spondylolisthesis.
Authors:Seuk JW, Bae J, Shin SH, Lee SH
Institution:Department of Neurosurgery, Chungdam Wooridul Spine Hospital, Seoul, Republic of Korea. Korea. Electronic address: jsbaemd@gmail.com. Korea. Korea.
Journal:World Neurosurg. 2018 Sep;117:e493-e499. doi: 10.1016/j.wneu.2018.06.063. Epub 2018 Jun 18.

9:Surgical Outcomes of Single-Level Transforaminal Lumbar Interbody Fusion for Degenerative Spondylolisthesis With and Without Kyphotic Alignment.
Authors:Zhu C, Qiu X, Zhuang M, Cheng D, Liu Z
Institution:Department of Spine Surgery, The Third Affiliated Hospital of Soochow University, Changzhou, China. Electronic address: drzhiweiliu@126.com.
Journal:World Neurosurg. 2018 Sep;117:e396-e402. doi: 10.1016/j.wneu.2018.06.042. Epub 2018 Jun 15.

10:The Effect of Cigarette Smoking on Wound Complications After Single-Level Posterolateral and Interbody Fusion for Spondylolisthesis.
Authors:Echt M, De la Garza Ramos R, Nakhla J, Gelfand Y, Cezayirli P, Holland R, Kinon MD, Yassari R
Institution:Spine Research Group, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York, USA; Department of Neurological Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York, USA. Electronic address: ryassari@montefiore.org.
Journal:World Neurosurg. 2018 Aug;116:e824-e829. doi: 10.1016/j.wneu.2018.05.103. Epub 2018 May 23.

11:The effectiveness and safety of nonsurgical integrative interventions for symptomatic lumbar spinal spondylolisthesis: A randomized controlled multinational, multicenter trial protocol.
Authors:Kim K, Youn Y, Lee SH, Choi JC, Jung JE, Kim J, Qu W, Eldrige J, Kim TH
Institution:Department of Spine Center, Mokhuri Neck and Back Hospital, Seoul. MN, USA. MN, USA. University, Seoul, Republic of Korea.
Journal:Medicine (Baltimore). 2018 May;97(19):e0667. doi: 10.1097/MD.0000000000010667.

12:Effect of PLIF and TLIF on sagittal spinopelvic balance of patients with degenerative spondylolisthesis.
Authors:Uysal M, Ozalay M, Derincek A, Kochai A, Turker M
Institution:Department of Orthopedics and Traumatology, Sakarya University Faculty of Medicine, Sakarya, Turkey. University School of Medicine, Adana, Turkey. Turkey. Medicine, Sakarya, Turkey. Electronic address: alkoc79@gmail.com. Medicine, Sakarya, Turkey.
Journal:Acta Orthop Traumatol Turc. 2018 Jul;52(4):272-276. doi: 10.1016/j.aott.2018.03.001. Epub 2018 Apr 26.

13:Comparisons of direct costs, outcomes, and cost-utility of decompression surgery with fusion versus decompression alone for degenerative lumbar spondylolisthesis.
Authors:Yagi M, Fujita N, Okada E, Tsuji O, Nagoshi N, Tsuji T, Nakamura M, Matsumoto M, Watanabe K
Institution:Department of Orthopedic Surgery, Keio University School of Medicine, Japan; Department of Orthopedic Surgery, National Hospital Organization Murayama Medical Center, Japan; Keio Spine Research Group (KSRG), Japan.; Department of Orthopedic Surgery, Keio University School of Medicine, Japan; Keio Spine Research Group (KSRG), Japan. Electronic address: watakota@gmail.com.; Department of Orthopedic Surgery, Fujita Health University, Japan; Keio Spine Research Group (KSRG), Japan.
Journal:J Orthop Sci. 2018 Jul;23(4):653-657. doi: 10.1016/j.jos.2018.04.001. Epub 2018 Apr 24.

14:Minimally invasive spinal decompression for degenerative lumbar spondylolisthesis and stenosis maintains stability and may avoid the need for fusion.
Authors:Minamide A, Yoshida M, Simpson AK, Nakagawa Y, Iwasaki H, Tsutsui S, Takami M, Hashizume H, Yukawa Y, Yamada H
Institution:Department of Orthopaedic Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, Wakayama 641-8510, Japan.; Microendoscopic Spine Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Journal:Bone Joint J. 2018 Apr 1;100-B(4):499-506. doi: 10.1302/0301-620X.100B4.BJJ-2017-0917.R1.

15:Does Preoperative Degenerative Spondylolisthesis Influence Outcome in Degenerative Lumbar Spinal Stenosis? Three-Year Results of a Swiss Prospective Multicenter Cohort Study.
Authors:Ulrich NH, Gravestock I, Held U, Schawkat K, Pichierri G, Wertli MM, Winklhofer S, Farshad M, Porchet F, Steurer J, Burgstaller JM
Institution:Department of Orthopedics and Neurosurgery, Spine Center, Schulthess Clinic, Zurich, Switzerland; Horten Centre for Patient Oriented Research and Knowledge Transfer, University of Zurich, Zurich, Switzerland. Electronic address: nils.hb.ulrich@gmail.com. Zurich, Zurich, Switzerland. Zurich, Zurich, Switzerland. University of Zurich, Zurich, Switzerland. Zurich, Zurich, Switzerland. Zurich, Zurich, Switzerland; Division of General Internal Medicine, Bern University Hospital, Bern University, Bern, Switzerland. University of Zurich, Zurich, Switzerland. Switzerland. Zurich, Switzerland. Zurich, Zurich, Switzerland. Zurich, Zurich, Switzerland.
Journal:World Neurosurg. 2018 Jun;114:e1275-e1283. doi: 10.1016/j.wneu.2018.03.196. Epub 2018 Apr 5.

16:Double-level lumbar spondylolysis and spondylolisthesis: A retrospective study.
Authors:Zhang S, Ye C, Lai Q, Yu X, Liu X, Nie T, Zhan H, Dai M, Zhang B
Institution:Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, No. 17 Yong Wai Zheng Street, Nanchang, Jiangxi, 330006, China. 1135547344@qq.com.; Nanchang University, Nanchang, Jiangxi, 330006, China.; Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, No. 17 Yong Wai Zheng Street, Nanchang, Jiangxi, 330006, China. acker11@126.com.
Journal:J Orthop Surg Res. 2018 Mar 16;13(1):55. doi: 10.1186/s13018-018-0723-3.

17:Does adding interbody fusion to posterolateral fusion increase success in the surgical management of degenerative lumbar spondylolisthesis?
Authors:Meissner-Haecker A, Urrutia J
Institution:Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile; Proyecto Epistemonikos, Santiago, Chile. Ortopedia, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile. Email: jurrutia@med.puc.cl. Address: Centro Evidencia UC, Pontificia Universidad Catolica de Chile, Centro de Innovacion UC Anacleto Angelini, Avda. Vicuna Mackenna 4860, Macul, Santiago, Chile.
Journal:Medwave. 2018 Jan 30;18(1):e7147. doi: 10.5867/medwave.2018.01.7146.

18:Postoperative Opioid Use, Complications, and Costs in Surgical Management of Lumbar Spondylolisthesis.
Authors:Vail D, Azad TD, O'Connell C, Han SS, Veeravagu A, Ratliff JK
Institution:Department of Neurosurgery.
Journal:Spine (Phila Pa 1976). 2018 Aug 1;43(15):1080-1088. doi: 10.1097/BRS.0000000000002509.

19:Which Domains of the ODI Best Predict Change in Physical Function in Patients After Surgery for Degenerative Lumbar Spondylolisthesis?
Authors:Murphy HA, Warnick E, McEntee R, Nicholson K, Hollern DA, Stawicki C, Tarazona D, Schroeder GD, Woods BI, Kurd MF, Rihn JA, Anderson GD, Kepler CK, Hilibrand AS, Vaccaro AR, Radcliff KE
Institution:The Rothman Institute at Thomas Jefferson University, Philadelphia, PA.
Journal:Spine (Phila Pa 1976). 2018 Jun 1;43(11):805-812. doi: 10.1097/BRS.0000000000002459.

20:Quality of Life and Slip Progression in Degenerative Spondylolisthesis Treated Nonoperatively.
Authors:Cushnie D, Johnstone R, Urquhart JC, Gurr KR, Bailey SI, Bailey CS
Institution:Division of Orthopaedics, Department of Surgery, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.; London Health Sciences Center, London, Ontario, Canada.; Lawson Health Research Institute, London, Ontario, Canada.
Journal:Spine (Phila Pa 1976). 2018 May 15;43(10):E574-E579. doi: 10.1097/BRS.0000000000002429.

21:Circumferential fusion: a comparative analysis between anterior lumbar interbody fusion with posterior pedicle screw fixation and transforaminal lumbar interbody fusion for L5-S1 isthmic spondylolisthesis.
Authors:Tye EY, Tanenbaum JE, Alonso AS, Xiao R, Steinmetz MP, Mroz TE, Savage JW
Institution:Center for Spine Health, Cleveland Clinic, 9500 Euclid Ave, S-40, Cleveland, OH 44195, USA; Case Western Reserve University School of Medicine, 9500 Euclid Ave, S-40, Cleveland, OH 44195, USA; Department of Orthopaedic Surgery, Cleveland Clinic, 9500 Euclid Ave, S-40, Cleveland, OH 44195, USA. Electronic address: eyt4@case.edu.; Center for Spine Health, Cleveland Clinic, 9500 Euclid Ave, S-40, Cleveland, OH 44195, USA; Case Western Reserve University School of Medicine, 9500 Euclid Ave, S-40, Cleveland, OH 44195, USA; Department of Orthopaedic Surgery, Cleveland Clinic, 9500 Euclid Ave, S-40, Cleveland, OH 44195, USA; Department of Epidemiology and Biostatistics, Case Western Reserve University School of Medicine, 9500 Euclid Ave, S-40, Cleveland, OH 44195, USA.; Center for Spine Health, Cleveland Clinic, 9500 Euclid Ave, S-40, Cleveland, OH 44195, USA; Case Western Reserve University School of Medicine, 9500 Euclid Ave, S-40, Cleveland, OH 44195, USA; Department of Neurosurgery, Cleveland Clinic, 9500 Euclid Ave, S-40, Cleveland, OH 44195, USA.; Center for Spine Health, Cleveland Clinic, 9500 Euclid Ave, S-40, Cleveland, OH 44195, USA; Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, 9500 Euclid Ave, S-40, Cleveland, OH 44195, USA.; Center for Spine Health, Cleveland Clinic, 9500 Euclid Ave, S-40, Cleveland, OH 44195, USA; Department of Neurosurgery, Cleveland Clinic, 9500 Euclid Ave, S-40, Cleveland, OH 44195, USA; Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, 9500 Euclid Ave, S-40, Cleveland, OH 44195, USA.
Journal:Spine J. 2018 Mar;18(3):464-471. doi: 10.1016/j.spinee.2017.08.227. Epub 2017 Aug 15.

22:A retrospective review comparing two-year patient-reported outcomes, costs, and healthcare resource utilization for TLIF vs. PLF for single-level degenerative spondylolisthesis.
Authors:Kim E, Chotai S, Stonko D, Wick J, Sielatycki A, Devin CJ
Institution:Department of Orthopaedic Surgery, Vanderbilt Spine Institute, Vanderbilt University School of Medicine, Medical Center East, South Tower, Suite 4200, Nashville, TN, 37232-8774, USA. clintondevin@gmail.com.
Journal:Eur Spine J. 2018 Mar;27(3):661-669. doi: 10.1007/s00586-017-5142-3. Epub 2017 Jun 5.

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"The MediFocus Guidebook on Spondylolisthesis provided me with the information I needed to make an informed decision regarding my treatment. The Guidebook clearly explained the various grades of spondylolisthesis and what patients can expect at each stage. The various treatment options are also clearly explained so that you walk away with a much more realistic expectation about what to expect after treatment."
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