March 2022 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Spondylolisthesis abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Spondylolisthesis. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Spondylolisthesis. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Spondylolisthesis every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.

1:Comparison between Oblique Lumbar Interbody Fusion (OLIF) and Minimally Invasive Transforaminal Lumbar Interbody Fusion (MISTLIF) for Lumbar Spondylolisthesis.
Authors:Chandra VVR, M Prasad BC, Hanu TG, Kale PG
Institution:Department of Neurosurgery, Sri Venkateswara Institute of Medical Sciences (SVIMS), Tirupati, Chittoor Dist., Andhra Pradesh, India.
Journal:Neurol India. 2022 Jan-Feb;70(1):127-134. doi: 10.4103/0028-3886.338732.

2:Lumbar Spinal Stenosis with Degenerative Spondylolisthesis Treated with Decompression Alone. A Cohort of 346 Patients at a Large Spine Unit. Clinical Outcome, Complications and Subsequent Surgery.
Authors:Pazarlis K, Frost A, Försth P
Institution:Stockholm Spine Center, Upplands Vasby, Sweden. Department of Surgical Sciences, Division of Orthopaedics, Uppsala University, Uppsala, Sweden.
Journal:Spine (Phila Pa 1976). 2022 Mar 15;47(6):470-475. doi: 10.1097/BRS.0000000000004291.

3:Respective Correction Rates of Lateral Lumbar Interbody Fusion and Percutaneous Pedicle Screw Fixation for Lumbar Degenerative Spondylolisthesis.
Authors:Isogai N, Yoshida K, Shiono Y, Sasao Y, Funao H, Ishii K
Institution:Department of Orthopaedic Surgery, School of Medicine, International University of Health and Welfare (IUHW), Chiba 286-8520, Japan.
Journal:Medicina (Kaunas). 2022 Jan 23;58(2):169. doi: 10.3390/medicina58020169.

4:Comparison of the clinical efficacy of two fixation methods combined with OLIF in the treatment of lumbar spondylolisthesis in adult patients.
Authors:Zhang X, Guo Y, Li Y
Institution:Department of Spine Surgery, Xi'an Jiaotong University Affiliated Honghui Hospital, Xi'an, 710000, Shaanxi, China. max701ml@163.com.
Journal:J Orthop Surg Res. 2022 Feb 21;17(1):115. doi: 10.1186/s13018-022-02991-z.

5:Isthmic spondylolisthesis treated with circumferential arthrodesis (ALIF and posterior fixation): correction, fusion and indirect decompression.
Authors:Khalifé M, Dauzac C, Lenoir T, Magrino B
Journal:Acta Orthop Belg. 2021 Dec;87(4):787-794. doi: 10.52628/87.4.27.

6:A retrospective comparative study of postoperative sagittal balance in isthmic L5-S1 spondylolisthesis using single segment or two-segment pedicle screw fixation.
Authors:Shao X, Liu H, Wu J, Qian Z, Qu R, Liu T
Institution:Department of Orthopedic Surgery, The First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Suzhou, Jiangsu, 215006, P.R. China. liutaodoctor@163.com.
Journal:BMC Musculoskelet Disord. 2022 Feb 12;23(1):145. doi: 10.1186/s12891-022-05098-y.

7:Degenerative Spondylolisthesis: A Narrative Review.
Authors:Akkawi I, Zmerly H
Institution:Villa Erbosa Hospital 50/2, 40129, Bologna, Italy. i.akkawi@libero.it. Ludes Lugano Campus, Lugano, Switzerland. zmerly@msn.com.
Journal:Acta Biomed. 2022 Jan 19;92(6):e2021313. doi: 10.23750/abm.v92i6.10526.

8:Isthmic Spondylolisthesis is Associated with Less Revisions for Adjacent Segment Disease After Lumbar Spine Fusion Than Degenerative Spinal Conditions: A 10-Year Follow-Up Study.
Authors:Toivonen LA, Mäntymäki H, Häkkinen A, Kautiainen H, Neva MH
Institution:Department of Orthopaedics and Trauma, University of Tampere, Faculty of Medicine and Life Sciences and Tampere University Hospital, Tampere, Finland.
Journal:Spine (Phila Pa 1976). 2022 Feb 15;47(4):303-308. doi: 10.1097/BRS.0000000000004242.

9:A systematic review and meta-analysis of the clinical efficacy of anterior lumbar interbody fusion in the treatment of orthopedic spondylolisthesis.
Authors:Xu X, Li X, Yang T
Institution:Department of Orthopedic Surgery, Fifth People's Hospital of Chongqing, University of Chinese Academy of Sciences Chongqing Renji Hospital, Chongqing, China. Chongqing Municipality Clinical Research Center for Geriatric Diseases, Chongqing University Three Gorges Hospital, Chongqing, China.
Journal:Ann Palliat Med. 2021 Dec;10(12):12607-12617. doi: 10.21037/apm-21-3330.

10:Comparison of degenerative lumbar spondylolisthesis and isthmic lumbar spondylolisthesis: effect of pedicle screw placement on proximal facet invasion in surgical treatment.
Authors:Wang PT, Zhang JN, Liu TJ, Yang JS, Hao DJ
Institution:Spine Surgery, Honghui Hospital Affiliated, Xi'an Jiaotong University, Xi'an City, 710054, Shaanxi Province, China. hdjhhyy@126.com.
Journal:BMC Musculoskelet Disord. 2022 Jan 3;23(1):6. doi: 10.1186/s12891-021-04962-7.

11:Comparison of L5 pedicle morphology in patients with and without L5 spondylolysis.
Authors:Baker JF
Institution:Department of Surgery, University of Auckland, Auckland, New Zealand.
Journal:Clin Anat. 2022 Mar;35(2):222-227. doi: 10.1002/ca.23821. Epub 2021 Dec 12.

12:Direct medical costs after surgical or nonsurgical treatment for degenerative lumbar spinal disease: A nationwide matched cohort study with a 10-year follow-up.
Authors:Kim CH, Chung CK, Choi Y, Lee J, Yang SH, Lee CH, Park SB, Kim KT, Rhee JM, Park MS
Institution:Department of Neurosurgery, Seoul National University Hospital, Seoul, Republic of Korea. Department of Orthopedics, Hallym University Dongtan Sacred Heart Hospital, Gyeonggi, Republic of Korea.
Journal:PLoS One. 2021 Dec 1;16(12):e0260460. doi: 10.1371/journal.pone.0260460. eCollection 2021.

13:Clinical Outcomes of Percutaneous Endoscopic Lumbar Discectomy for the Treatment of Grade I and Grade II Degenerative Lumbar Spondylolisthesis: A Retrospective Study With a Minimum Five-Year Follow-up.
Authors:Wu Q, Yuan S, Fan N, Du P, Li J, Yang L, Zhu W, Zang L
Institution:Department of Orthopedics, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Journal:Pain Physician. 2021 Dec;24(8):E1291-E1298.

14:Clinical characteristic and surgical treatment of traumatic lumbar spondylolisthesis: A series of 28 patients.
Authors:Hu Y, Zhang KL, Zhu BK, Zhong JB, Yuan ZS, Dong WX, Sun XY, Wu JD
Institution:Department of Spine surgery, The Ningbo No.6 Hospital, Ningbo, 315040, Zhejiang Province, China. Electronic address: huyong610@163.com. Medical School of Ningbo University, Ningbo, 315040, Zhejiang Province, China.
Journal:Injury. 2022 Mar;53(3):1094-1097. doi: 10.1016/j.injury.2021.09.049. Epub 2021 Oct 10.

15:Incidence of and risk factors for spondylolisthesis, scoliosis, and vertebral fracture in rheumatoid arthritis.
Authors:Yamada K, Suzuki A, Takahashi S, Inui K, Koike T, Okano T, Yabu A, Hori Y, Toyoda H, Nakamura H
Institution:Department of Orthopaedic Surgery, PL Hospital, 2204, Shindo, Tondabayashi City, Osaka, 584-8585, Japan. yamachen@med.osaka-cu.ac.jp. Department of Orthopaedic Surgery, Osaka City University, Osaka City, Osaka, Japan.
Journal:J Bone Miner Metab. 2022 Jan;40(1):120-131. doi: 10.1007/s00774-021-01261-y. Epub 2021 Aug 23.

16:Comparison of cost and complication rates for profiling hospital performance in lumbar fusion for spondylolisthesis.
Authors:Greenberg JK, Olsen MA, Dibble CF, Zhang JK, Pennicooke BH, Yamaguchi K, Kelly MP, Hall BL, Ray WZ
Institution:Departments of Neurological Surgery. Electronic address: jacobgreenberg@wustl.edu. Corporation, St. Louis, MO.
Journal:Spine J. 2021 Dec;21(12):2026-2034. doi: 10.1016/j.spinee.2021.06.014. Epub 2021 Jun 20.

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