May 2020 Issue

Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.

Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Spondylolisthesis abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Spondylolisthesis. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Spondylolisthesis. You can access the summaries of each article referenced below by simply clicking on the article Title.

We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Spondylolisthesis every 3 months. Thank you for your ongoing subscription to this publication.

Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.

1:A Bayesian network meta-analysis of 5 different fusion surgical procedures for the treatment of lumbar spondylolisthesis.
Authors:Tang L, Wu Y, Jing D, Xu Y, Wang C, Pan J
Journal:Medicine (Baltimore). 2020 Apr;99(14):e19639. doi: 10.1097/MD.0000000000019639.

2:Association of MRI-defined lumbar paraspinal muscle mass and slip percentage in degenerative and isthmic spondylolisthesis: A multicenter, retrospective, observational study.
Authors:Park JH, Kim KW, Youn Y, Kim H, Chung WS, Song MY, Cho JH
Institution:Department of Korean Rehabilitation Medicine, College of Korean Medicine, Kyung-Hee University.
Journal:Medicine (Baltimore). 2019 Dec;98(49):e18157. doi: 10.1097/MD.0000000000018157.

3:A ball-slide-type interbody distractor is effective in posterior reduction and internal fixation for patients with mid- to high-grade isthmic spondylolisthesis enrolled in a randomized clinical trial.
Authors:Li P, Zhao Z, Jia N, Wang L, Sun Z, Jin X
Institution:Department of Neurosurgery, The Second Hospital of Hebei Medical University, Shijiazhuang. Department of Orthopaedics, Harrison International Peace Hospital of Hebei Medical University, Hengshui.
Journal:Medicine (Baltimore). 2019 Nov;98(47):e17947. doi: 10.1097/MD.0000000000017947.

4:Comparative Sacral Morphology in Spondylolisthesis Patients.
Authors:Hresko MT, Deckey DG, Hinchcliff E, Kalish LA
Institution:Department of Orthopaedic Surgery, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA. Electronic address: timothy.hresko@childrens.harvard.edu. Department of Orthopaedic Surgery, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA; Institutional Centers for Clinical and Translational Research, Boston
Journal:Spine Deform. 2019 Nov;7(6):945-949. doi: 10.1016/j.jspd.2019.03.008.

5:Complications with Minimally Invasive Transforaminal Lumbar Interbody Fusion for Degenerative Spondylolisthesis in the Obese Population.
Authors:Buyuk AF, Shafa E, Dawson JM, Schwender JD
Institution:Twin Cities Spine Center, Minneapolis, MN.
Journal:Spine (Phila Pa 1976). 2019 Dec 1;44(23):E1401-E1408. doi: 10.1097/BRS.0000000000003160.

6:Perioperative Risk Factors for Early Revisions in Stand-Alone Lateral Lumbar Interbody Fusion.
Authors:Rentenberger C, Okano I, Salzmann SN, Winter F, Plais N, Burkhard MD, Shue J, Sama AA, Cammisa FP, Girardi FP, Hughes AP
Institution:Hospital for Special Surgery, New York, New York, USA. Electronic address: hughesa@hss.edu.
Journal:World Neurosurg. 2020 Feb;134:e657-e663. doi: 10.1016/j.wneu.2019.10.164. Epub 2019 Nov 4.

7:Patients undergoing surgery for lumbar spinal stenosis experience unique courses of pain and disability: A group-based trajectory analysis.
Authors:Hebert JJ, Abraham E, Wedderkopp N, Bigney E, Richardson E, Darling M, Hall H, Fisher CG, Rampersaud YR, Thomas KC, Jacobs B, Johnson M, Paquet J, Attabib N, Jarzem P, Wai EK, Rasoulinejad P, Ahn H, Nataraj A, Stratton A, Manson N
Institution:Faculty of Kinesiology, University of New Brunswick, Fredericton, Canada. Canada East Spine Centre, Saint John, New Brunswick, Canada.
Journal:PLoS One. 2019 Nov 7;14(11):e0224200. doi: 10.1371/journal.pone.0224200. eCollection 2019.

8:High grade isthmic spondylolisthesis; can reduction always re-align the unbalanced pelvis?
Authors:Martikos K, Greggi T, Faldini C
Institution:Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136, Bologna, Italy. info@martikos.com.
Journal:BMC Musculoskelet Disord. 2019 Oct 29;20(1):499. doi: 10.1186/s12891-019-2865-9.

9:The correlation between sagittal spinopelvic alignment and degree of lumbar degenerative spondylolisthesis.
Authors:Nakamae T, Nakanishi K, Kamei N, Adachi N
Institution:Department of Orthopedic Surgery, Integrated Health Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima, 734-8551, Japan.
Journal:J Orthop Sci. 2019 Nov;24(6):969-973. doi: 10.1016/j.jos.2019.08.021. Epub 2019 Sep 21.

10:Reverse Bohlman technique for treatment of high-grade spondylolisthesis in an adult population.
Authors:Jamshidi A, Levi AD
Institution:Department of Neurological Surgery and the Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, FL, USA. Electronic address: ALevi@med.miami.edu.
Journal:J Clin Neurosci. 2019 Nov;69:230-236. doi: 10.1016/j.jocn.2019.07.044. Epub 2019 Aug 19.

11:Do We Have Adequate Flexion-extension Radiographs for Evaluating Instability in Patients With Lumbar Spondylolisthesis?
Authors:Morita T, Yoshimoto M, Terashima Y, Tanimoto K, Iesato N, Ogon I, Oshigiri T, Teramoto A, Emori M, Takashima H, Hirota R, Fujimoto S, Yamashita T
Institution:Department of Orthopedic Surgery, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan.
Journal:Spine (Phila Pa 1976). 2020 Jan 1;45(1):48-54. doi: 10.1097/BRS.0000000000003203.

12:Grade II Spondylolisthesis: Reverse Bohlman Procedure with Transdiscal S1-L5 and S2 Alar Iliac Screws Placed with Robotic Guidance.
Authors:Ho AL, Varshneya K, Medress ZA, Pendharkar AV, Sussman ES, Cheng I, Veeravagu A
Institution:Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA. Electronic address: Anandv2@stanford.edu.
Journal:World Neurosurg. 2019 Dec;132:421-428.e1. doi: 10.1016/j.wneu.2019.07.229. Epub 2019 Aug 6.

13:Incidence, Prevalence, and Analysis of Risk Factors for Surgical Site Infection After Lumbar Fusion Surgery: ‚Č•2-Year Follow-Up Retrospective Study.
Authors:Li Z, Liu P, Zhang C, Xu G, Zhang Y, Chang Y, Liu M, Hou S
Institution:Department of Orthopaedics, First Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China; Key Laboratory of Molecular Mechanism for Repair and Remodeling of Orthopaedic Di Department of Orthopaedics, Fourth Medical Center of PLA General Hospital, Beijing, People's Republic of China.
Journal:World Neurosurg. 2019 Nov;131:e460-e467. doi: 10.1016/j.wneu.2019.07.207. Epub 2019 Aug 5.

14:Association Between Irregular Alteration of Facet Orientation and Degenerative Lumbar Spondylolisthesis.
Authors:Wang H, Wu Z
Institution:Department of Spinal Surgery, General Hospital of Southern Theatre Command of PLA, Guangzhou, China. Electronic address: Zenghuiwu_1@163.com.
Journal:World Neurosurg. 2019 Nov;131:e298-e302. doi: 10.1016/j.wneu.2019.07.141. Epub 2019 Jul 26.

15:Disability, emotional distress and well-being among patients with lumbar spondylolisthesis.
Authors:Hsu HC, Chang CJ, Tung HH, Wang TJ
Institution:Department of Nursing, Cathay General Hospital, Taipei City, Taiwan. School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei City, Taiwan.
Journal:J Clin Nurs. 2019 Nov;28(21-22):3866-3878. doi: 10.1111/jocn.14992. Epub 2019 Jul 29.

16:Predictors of L4-L5 Degenerative Lumbar Spondylolisthesis: L4 Inclination Angle and Facet Joint Angle.
Authors:Guo M, Kong C, Sun S, Sun X, Li X, Lu S
Institution:Department of Orthopedics, Capital Medical University, Xuanwu Hospital, Beijing, China. Electronic address: 13167513099@163.com.
Journal:World Neurosurg. 2019 Oct;130:e680-e686. doi: 10.1016/j.wneu.2019.06.188. Epub 2019 Jul 4.

17:In Degenerative Spondylolisthesis, Unilateral Laminotomy for Bilateral Decompression Leads to Less Reoperations at 5 Years When Compared to Posterior Decompression With Instrumented Fusion: A Propensity-matched Retrospective Analysis.
Authors:Kuo CC, Merchant M, Kardile MP, Yacob A, Majid K, Bains RS
Institution:Department of Spine Surgery, The Permanente Medical Group, 3600 Broadway Suite 15, Oakland, CA.
Journal:Spine (Phila Pa 1976). 2019 Nov 1;44(21):1530-1537. doi: 10.1097/BRS.0000000000003121.

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